One step closer to a DNA vaccine against dengue virus

(Frontiers) In a new study, researchers inoculated mice with a new DNA vaccine candidate (pVAX1-D1ME) in order to evaluate its efficiency. They found that the vaccine candidate was able to induce persistent humoral and cellular immune responses and provided efficient protection against lethal challenge from one of the four serotypes of dengue virus (DV1). These results are encouraging for the future development of a tetravalent vaccine that could provide efficient protection against all four ser...